There are many authentication methods being used in the industry:
1.Trusted Login – Majority people are using this authentication method, due to the design of many customers only using iManage Work within the company environment. With this authentication method, You cannot open up your environment for external connections. This system relies on a trusted pre-authentication by the login manager. Therefore this feature is not recommended to use in high-security environments, however, It can be more secure with Kerberos. Further, this authentication method is not compliant with Work 10 and not supported within the iManage Cloud.
2. Explicit Login- This is a straightforward authentication method where user credentials are authenticating against iManage libraries. The disadvantage of this authentication method is that users need to manage another set of credentials. One would be managing users credentials within control center as well as enabling, disabling and adding users. Active directory does not federate it if you disable someone in an active directory they still might be able to login to iManage unless you disable them within control center.